Chiral metal nanozyme-enabled SOD2 activation and siRNA delivery cooperatively mitigating chronic heart failure
Wang Z, Zhang R, Hu Y, Song Q, Fu X, Wang Y, Chen M, Fan K, Fan C, Sun D. Chiral metal nanozyme-enabled SOD2 activation and siRNA delivery cooperatively mitigating chronic heart failure. Bioact Mater. 2025 Dec 9;58:203-220.
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心血管疾病
2025
Pyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart
Wang Y, Guo D, Zhu J, Yang X, Wu C, Geng J, Liang Q, Sun N, Niu X, Liu Y, Guo Y, Chang P, Li Y, Hu L. Pyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart. Nat Commun. 2026 Mar 14;17(1):3929.
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2026
ARMH4 accelerates aging by maintaining a positive-feedback growth signaling circuit.
Fang Y, Wang B, Guo Q, Lv J, Li J, Wang J, Guo N, Bai Y, Xu A, Ma X, Tan H, Li H, Wang Z. ARMH4 accelerates aging by maintaining a positive-feedback growth signaling circuit. Nat Commun. 2025 Dec 14;17(1):812.
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心血管疾病
2025
Cold exposure-induced β-hydroxybutyrate promotes brown fat mitochondrial lipid droplet contact to ameliorate fatty dysfunction and hepatic steatosis
Yu Y, An N, Chen Y, Tong M, Liu S, Li Y, Dong H, Li Y, Feng M, Liu L, Cao S, Chen H, Zhao Y, Du Z, Zhao X, Yang B, Zhang Y. Cold exposure-induced β-hydroxybutyrate promotes brown fat mitochondrial lipid droplet contact to ameliorate fatty dysfunction and hepatic steatosis. Acta Pharm Sin B. 2026 Feb;16(2):930-947.
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代谢
2025
Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis-Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis
He R, Wu B, Han L, Li M, Guo W, Fu J, Mei B, Gross ER, Liu X, Lu Y. Activation of Spinal Astrocyte α2A Adrenoceptors Protects Against Sepsis-Induced Heart Injury Through Inhibition of GABAergic Neuronal Necroptosis. Adv Sci (Weinh). 2025 Oct;12(39):e04406.
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心血管疾病
2025
Bioabsorbable Endovascular Adhesive Tape (BEAT) for Improving Vascular Regeneration
Wang J, Wang J, Li X, Yu B, Chen Y, Guo Y, Qian H, Hu M, Liu H, Liu W, Xu H, Ren K, Martins MCL, Ji J. Bioabsorbable Endovascular Adhesive Tape (BEAT) for Improving Vascular Regeneration. Adv Sci (Weinh). 2026 Apr;13(22):e12857.
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心血管疾病
2026
