Pyruvate Dehydrogenase Kinase 4 Underlies the Metabolic Disorder of Cardiomyocytes in Patients With Hypertrophic Cardiomyopathy From Hypertrophy to Heart Failure
Hua X, Sun Z, Wang C, Cui H, Shan D, Tao M, Cui Z, Chang Y, Bao M, Mo H, Chen X, Song J. Pyruvate Dehydrogenase Kinase 4 Underlies the Metabolic Disorder of Cardiomyocytes in Patients With Hypertrophic Cardiomyopathy From Hypertrophy to Heart Failure. J Am Heart Assoc. 2025 Aug 5;14(15):e041401.
小鼠
心血管疾病
2025
Jaranol: a compound with therapeutic activity against pathological cardiac remodelling via multi-target inhibition of the Snai3/TLR2 and NF-κB signaling pathways
Zhang Y, Li N, Chu S, Fu H, Yang X, Xia H, Xiao Y, Xiao Z, Liu J, Dong Y, Liu T. Jaranol: a compound with therapeutic activity against pathological cardiac remodelling via multi-target inhibition of the Snai3/TLR2 and NF-κB signaling pathways. Front Pharmacol. 2026 Jan 2;16:1723889.
小鼠
心血管疾病
2026
Ultrasound combined with microbubble enhanced renoprotective effects of NLRP3 inflammasome inhibitor MCC950 in CKD model
Wen W, Tu B, Ren X, Liu Y, Jiang R, Wu X, Liu J. Ultrasound combined with microbubble enhanced renoprotective effects of NLRP3 inflammasome inhibitor MCC950 in CKD model. Front Pharmacol. 2025 Jul 31;16:1616542.
小鼠
心血管疾病
2025
The Bioinformatics Analysis of Publicly Available Datasets and Validation in a Mouse Model of Myocardial Infarction Through Coronary Artery Ligation
Sun H, Liu F, Sun M, Wang W, Wang J, Wang H, Jiang X, Ding X, Wang C, Zhong L. The Bioinformatics Analysis of Publicly Available Datasets and Validation in a Mouse Model of Myocardial Infarction Through Coronary Artery Ligation. J Inflamm Res. 2026 Jan 6;19:558274.
小鼠
心血管疾病
2026
Optimization strategies for reversible myocardial injury caused by ultrasonic cavitation effects using an orthogonal experimental design
Zhao L, Li X, Huang D, Zhao Y, Cao H, Liao C, Yuan Y, Xi X, Li S, Zhang B. Optimization strategies for reversible myocardial injury caused by ultrasonic cavitation effects using an orthogonal experimental design. Sci Rep. 2025 Nov 11;15(1):39471.
大小鼠
心血管疾病
2025
Pathogenic glycosyltransferase genes and potential therapeutic drugs in pressure overload-induced heart failure
Wu J, Lu Y, Gao X, Hu X, Lu Z, Li C. Pathogenic glycosyltransferase genes and potential therapeutic drugs in pressure overload-induced heart failure. ESC Heart Fail. 2025 Dec;12(6):4108-4124.
小鼠
心血管疾病
2025
