Ginsenoside Rb1 ameliorates post-doxorubicin treatment myocardial hypertrophy via CaN/NFATc4/GATA4
Chang JJ, Xu LX, Yi WJ, Zhang HH, Zhang JW, Zheng B, Fu PY, He RL, Wang RX, Jiang JF, Gui LX, Wu MX, Lin JJ, Huang ZH, Song JL, Lin MJ, Jiao HX, Wu ZJ. Ginsenoside Rb1 ameliorates post-doxorubicin treatment myocardial hypertrophy via CaN/NFATc4/GATA4. J Ginseng Res. 2025 Sep;49(5):585-593.
小鼠
心血管疾病
2025
Pyruvate Dehydrogenase Kinase 4 Underlies the Metabolic Disorder of Cardiomyocytes in Patients With Hypertrophic Cardiomyopathy From Hypertrophy to Heart Failure
Hua X, Sun Z, Wang C, Cui H, Shan D, Tao M, Cui Z, Chang Y, Bao M, Mo H, Chen X, Song J. Pyruvate Dehydrogenase Kinase 4 Underlies the Metabolic Disorder of Cardiomyocytes in Patients With Hypertrophic Cardiomyopathy From Hypertrophy to Heart Failure. J Am Heart Assoc. 2025 Aug 5;14(15):e041401.
小鼠
心血管疾病
2025
IDO-1 Promotes Pulmonary Vascular Remodeling Via Kynurenine Pathway in Pulmonary Arterial Hypertension
Cai Z, Tu L, Tian S, Deng L, Fu Y, Phan C, van den Bosch TPP, Tran-Lundmark K, Nagy BM, Olschewski H, Li X, Wang S, Wang D, Yan Y, Fu L, Boomars KA, Guignabert C, Merkus D. IDO-1 Promotes Pulmonary Vascular Remodeling Via Kynurenine Pathway in Pulmonary Arterial Hypertension. J Am Heart Assoc. 2025 Aug 19;14(16):e040896.
大鼠
心血管疾病
2025
Fibroblast-Derived Microfibrillar-Associated Protein 5 Exerts Cardioprotective Effects After Myocardial Infarction by Activating the NOTCH2 Signaling in Cardiomyocytes
Guo J, Gu Z, Lin M, Tao H, Jiang Y, Zhang R, Jia D, Zhang N, You S, Sun Y, Jia P. Fibroblast-Derived Microfibrillar-Associated Protein 5 Exerts Cardioprotective Effects After Myocardial Infarction by Activating the NOTCH2 Signaling in Cardiomyocytes. J Am Heart Assoc. 2026 Mar 3;15(5):e045111.
小鼠
心血管疾病
2026
Integrative Machine Learning and Experimental Validation Identify FIS1 as a Candidate Biomarker Linked to Mitochondrial Dynamics in Pulmonary Hypertension
Zhang Y, Dai Q, Gong L, Zheng R, Huang W, Wang F, Yuan R, Song L, Dai A. Integrative Machine Learning and Experimental Validation Identify FIS1 as a Candidate Biomarker Linked to Mitochondrial Dynamics in Pulmonary Hypertension. Cells. 2026 Feb 5;15(3):301.
小鼠
心血管疾病
2026
Electroacupuncture Pretreatment Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting Engulfment by Microglia in the Lateral Hypothalamus
Zhou X, Yang P, Dong C, Chang H, Zhang F, Shu Q, Wei N, Zhang B, Wu Y, Shao W, Cai R, Yu Q. Electroacupuncture Pretreatment Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting Engulfment by Microglia in the Lateral Hypothalamus. CNS Neurosci Ther. 2025 Sep;31(9):e70595.
小鼠
心血管疾病
2025
