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SERCA2 regulates Piezo1 channel activation and contributes to the cardiac function and baroreflex in mice

Zhao JX, Xu YZ, Fu HX, Li JQ, Yue M, Xu ZY, Li XL, Cui CP, Li BY. SERCA2 regulates Piezo1 channel activation and contributes to the cardiac function and baroreflex in mice. Acta Pharmacol Sin. 2025 Dec;46(12):3386-3395.

大鼠

心血管

2025

Defects in auxiliary fuel oxidation and mitochondrial pyruvate transport mark transition to overt heart failure in Tgαq*44 mice

Olkowicz M, Jedrzejewska A, Tyrankiewicz U, Fedak FA, Berkowicz P, Kwiatkowski G, Rosales-Solano H, Roy KS, Karas A, Krol O, Tomczyk M, Smolenski RT, Pawliszyn J, Chlopicki S. Defects in auxiliary fuel oxidation and mitochondrial pyruvate transport mark transition to overt heart failure in Tgαq*44 mice. J Transl Med. 2026 Mar 3;24(1):485.

小鼠

心血管疾病

2026

" Poge heart-saving decoction meliorates heart failure by suppressing apoptosis and fibrosis via regulation of the PI3K/AKT pathway"

Du L, Qin L, Zhou A, Ren Y, Wang S. Poge heart-saving decoction meliorates heart failure by suppressing apoptosis and fibrosis via regulation of the PI3K/AKT pathway. Front Pharmacol. 2026 Mar 25;17:1748420.

小鼠

心血管疾病

2026

Honey-fried licorice decoction ameliorates atrial fibrillation susceptibility by inhibiting the NOX2-ROS-TGF-β1 pathway

Qin Y, Wang J, Chen R, Tang Z, Zhi H, Wu X, Chen X, Fu J, Cai X, Shen J, Cao P, Zhou Q. Honey-fried licorice decoction ameliorates atrial fibrillation susceptibility by inhibiting the NOX2-ROS-TGF-β1 pathway. Front Pharmacol. 2025 Jul 23;16:1595111.

大鼠

心血管疾病

2025

Characterization of the effects of oxymatrine on myocardial hypertrophy in spontaneously hypertensive rats through transcriptomics and metabolomics

Li C, Li X, Tan J, Fang Q, Zhang M, Huang J. Characterization of the effects of oxymatrine on myocardial hypertrophy in spontaneously hypertensive rats through transcriptomics and metabolomics. Sci Rep. 2025 Sep 25;15(1):32810.

大鼠

心血管疾病

2025

Treadmill exercise ameliorates atherogenesis and vascular inflammation in ApoE-/- mice via circulating exosome-derived let-7c-5p

Guo W, Wang J, Chang Z, Lin S, Sha G, Wang S, Huang J, Hu M, Xia J. Treadmill exercise ameliorates atherogenesis and vascular inflammation in ApoE-/- mice via circulating exosome-derived let-7c-5p. Sci Rep. 2025 Dec 9;16(1):585.

小鼠

心血管疾病

2025

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