Higenamine Hydrochloride Ameliorates Diabetic Cardiomyopathy Through RhoA/MEK/ERK Pathway
Li Y, Wang L, Guan T, Chen Y, Zhu W, Liu X, Li Y, Huang H, Dong Z, Zhang H. Higenamine Hydrochloride Ameliorates Diabetic Cardiomyopathy Through RhoA/MEK/ERK Pathway. Inflammation. 2025 Dec 30;49(1):21.
小鼠
心血管疾病
2025
Sodium-Glucose Cotransporter 2 Inhibitor Ameliorate Angiotensin II-Induced Hypertension and Vascular Injury by Upregulating FGF21
Dai M, Jia Z, Wang H, Zheng P, Xue Y, Gong K, Zhao R. Sodium-Glucose Cotransporter 2 Inhibitor Ameliorate Angiotensin II-Induced Hypertension and Vascular Injury by Upregulating FGF21. Inflammation. 2025 Dec;48(6):4031-4045.
小鼠
心血管疾病
2025
Fasting Enhances Cardiomyocyte Hypoxia Tolerance by Regulating Ca2+ Transport at Mitochondria-Endoplasmic Reticulum Contact Sites.
Chen X, Jiao B, Xue T, Xie M, Yu Z. Fasting Enhances Cardiomyocyte Hypoxia Tolerance by Regulating Ca2+ Transport at Mitochondria-Endoplasmic Reticulum Contact Sites. Int J Mol Sci. 2026 Feb 24;27(5):2117.
大鼠
心血管疾病
2026
Jaranol: a compound with therapeutic activity against pathological cardiac remodelling via multi-target inhibition of the Snai3/TLR2 and NF-κB signaling pathways
Zhang Y, Li N, Chu S, Fu H, Yang X, Xia H, Xiao Y, Xiao Z, Liu J, Dong Y, Liu T. Jaranol: a compound with therapeutic activity against pathological cardiac remodelling via multi-target inhibition of the Snai3/TLR2 and NF-κB signaling pathways. Front Pharmacol. 2026 Jan 2;16:1723889.
小鼠
心血管疾病
2026
" Poge heart-saving decoction meliorates heart failure by suppressing apoptosis and fibrosis via regulation of the PI3K/AKT pathway"
Du L, Qin L, Zhou A, Ren Y, Wang S. Poge heart-saving decoction meliorates heart failure by suppressing apoptosis and fibrosis via regulation of the PI3K/AKT pathway. Front Pharmacol. 2026 Mar 25;17:1748420.
小鼠
心血管疾病
2026
Ultrasound combined with microbubble enhanced renoprotective effects of NLRP3 inflammasome inhibitor MCC950 in CKD model
Wen W, Tu B, Ren X, Liu Y, Jiang R, Wu X, Liu J. Ultrasound combined with microbubble enhanced renoprotective effects of NLRP3 inflammasome inhibitor MCC950 in CKD model. Front Pharmacol. 2025 Jul 31;16:1616542.
小鼠
心血管疾病
2025
